ELMSAN1 Products

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene. The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo. Chimera RNAi has many advantages over the conventional siRNAs. First, it has been demonstrated to have reliable knock-down for over 10,000 human genes. Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence. Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected. Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Entrez	91748 Human
Uniprot	NM_194278 Human NP_001036783 Human NP_001036783.1 Human Q6PJG2 Human
Product By Gene ID	91748
Alternate Names	c14_5541 C14orf117 C14orf43 chromosome 14 open reading frame 117 chromosome 14 open reading frame 43 ELM2 and Myb/SANT-like domain containing 1 ELMSAN1 FLJ00335 hypothetical protein LOC91748 LSR68 LSR68