eIF3e Products

Antibodies
eIF3e Antibody
eIF3e Antibody
NBP1-84869
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
eIF3e Antibody
eIF3e Antibody
NBP2-16298
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
eIF3e Antibody
eIF3e Antibody
NB110-85528
Species: Hu, Mu, Rt, Bv, Ca, Pm
Applications: WB, ELISA
Host: Rabbit Polyclonal
Lysates
eIF3e Overexpression Lysate ( ...
eIF3e Overexpression Lysate (Native)
NBL1-10192
Applications: WB
Proteins
Recombinant Human eIF3e Prote ...
Recombinant Human eIF3e Protein
H00003646-Q01
Species: Hu
Applications: WB, ELISA, PA
eIF3e Recombinant Protein Ant ...
eIF3e Recombinant Protein Antigen
NBP1-84869PEP
Species: Hu
Applications: AC
RNAi
eIF3e RNAi
eIF3e RNAi
H00003646-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Int6 is a candidate tumor suppressor in multiple neoplasms, and in particular, breast and lung cancers. The Int6 locus was initially identified as a common insertion site (CIS) in a genetic screen for transforming sequences in a breast cancer mouse model system. Insertion of mouse mammary tumor virus (MMTV) into this locus results in the production of an amino-terminal truncated gene product. Expression of the truncated Int6 product corresponds to cellular transformation in both in vivo and in vitro systems. This gene product plays a role in regulating translation initiation and is a component of the eIF3 translation initiation complex. There is evidence that suggests that Int6 may impart a negative role in the general translational machinery while promoting an increase in the expression of a subset of stressresponsive genes. Taken together, it is of great interest to further study the mechanism by which Int6 is involved in regulating cell growth.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 3646
Alternate Names
  • eIF-3 p48
  • murine mammary tumor integration site 6 (oncogene homolog)
  • Viral integration site protein INT-6 homolog
  • mammary tumor-associated protein INT6
  • Eukaryotic translation initiation factor 3 subunit 6
  • eukaryotic translation initiation factor 3, subunit 6 (48kD)
  • eIF3e
  • eukaryotic translation initiation factor 3 subunit E
  • eukaryotic translation initiation factor 3, subunit 6 48kDa
  • INT6eIF3-p46
  • EIF3S6EIF3-P48
  • eIF3-p48
  • eukaryotic translation initiation factor 3, subunit E

PTMs for eIF3e

Learn more about PTMs related to eIF3e.

Phosphorylation

Bioinformatics Tool for eIF3e

Discover related pathways, diseases and genes to eIF3e. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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