EGR1 Products

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi’s unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	1958
Alternate Names	AT225Transcription factor ETR103 early growth response 1 early growth response protein 1 EGR1 EGR-1 G0S30 KROX24 KROX-24 Nerve growth factor-induced protein A NGFIA NGFI-ATranscription factor Zif268 TIS8 ZIF-268 Zinc finger protein Krox-24 ZNF225 ZNF225Zinc finger protein 225

Research Areas for EGR1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Prostate Cancer
Transcription Factors and Regulators

Related EGR1 Blog Posts

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Synapsin I: Implicated in synaptic activity across a diverse range of studies Synapsins are a family of neuronal proteins that are most renowned for their activity in modulating the pre-synaptic terminal.  Synapsin’s behavior is regulated by protein kinases and phosphatases, which alter the way that synapsin’s i...    Read more.

No Monkey Business: APE1 is a Critical DNA Repair Enzyme APE1 (aka. HAP1, /Ref-1 or APEX) the mammalian ortholog of Escherichia coli Xth is a multifunctional protein possessing both DNA repair and transcriptional regulatory activity. APE1 acts essentially as master regulator of controlling cellular response...    Read more.

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