EDR1/PHC1 Products

Description

EDR1 / PHC1 is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq]

Bioinformatics

Entrez	1911 Human
Uniprot	NP_004417 Human NM_004426 Human AAH73964 Human AAH73964.1 Human
Product By Gene ID	1911
Alternate Names	EDR1 hPH1 Early development regulatory protein 1 PH1 early development regulator 1 (homolog of polyhomeotic 1) polyhomeotic-like protein 1 RAE28 polyhomeotic-like 1 HPH1 polyhomeotic-like 1 (Drosophila) polyhomeotic homolog 1 (Drosophila)

Diseases related to EDR1/PHC1

Discover more about diseases related to EDR1/PHC1.

Carcinoma
Embryonal Carcinoma
Malignant Neoplasms
Neoplasms
Immunologic Deficiency Syndromes
Lymphoma
Malignant Paraganglionic Neoplasm
Growth Arrest
Cell Transformation, Neoplastic
Crest Syndrome
Burkitt Lymphoma
Adenoma
Malignant Neoplasm Of Brain
Hypoxia
Collagen Arthritis
X-linked Combined Immunodeficiency Diseases
Injury To Kidney
Primary Immune Deficiency Disorder
Pituitary Diseases
Pituitary Neoplasms

Pathways for EDR1/PHC1

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Gene Silencing
Cell Cycle
Pathogenesis
Prophase
Cell Differentiation
Localization
Cell Adhesion
Cell Activation
Stem Cell Differentiation
T Cell Activation
Cell Cycle Arrest
Chromatin Organization
Interphase
Segmentation
Meiosis
Mitotic Prophase
Gastrulation
Cell Proliferation
Mitosis
Segment Specification

Research Areas for EDR1/PHC1

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Core ESC-Like Genes
Stem Cell Markers

PTMs for EDR1/PHC1

Learn more about PTMs related to EDR1/PHC1.

Methylation
Phosphorylation
Nitration

Bioinformatics Tool for EDR1/PHC1

Discover related pathways, diseases and genes to EDR1/PHC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.