EDF1 Products

Description

EDF1 encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene.

Bioinformatics

Entrez	8721 Human
Uniprot	NP_003783 Human NP_003783.1 Human AAH15500 Human AAH15500.1 Human NM_003792 Human
Product By Gene ID	8721
Alternate Names	multiprotein bridging factor-1 MBF1 multiprotein bridging factor 1 EDF-1Multiprotein-bridging factor 1 MGC9058 endothelial differentiation-related factor 1

Diseases related to EDF1

Discover more about diseases related to EDF1.

Tumor Angiogenesis
Malignant Neoplasms
Neoplasms
Hiv Infections
Malignant Neoplasm Of Breast
Immunologic Deficiency Syndromes
Kaposi Sarcoma
Leiomyosarcoma
Cardiac Hypertrophy
Malignant Tumor Of Colon
Malignant Neoplasm Of Lung
Sarcoma
Carcinoma
Mammary Neoplasms
Malignant Neoplasm Of Ovary
Epithelial Ovarian Cancer
Ovarian Neoplasm
Adenocarcinoma
Malignant Neoplasm Of Prostate

Pathways for EDF1

View related products by pathway and learn more about each of the pathways below.

Cell Differentiation
Endothelial Cell Differentiation
Cell Cycle
Angiogenesis
Cellular Homeostasis
Senescence
Cell Growth
Transport
Cell Proliferation
Larval Development
Pollination
Regulation Of Gene Expression
Abscission
Localization
Nuclear Transport
Organ Senescence
Response To Oxidative Stress
Floral Organ Senescence
Translation
Rna Interference

PTMs for EDF1

Learn more about PTMs related to EDF1.

Phosphorylation
Dephosphorylation

Bioinformatics Tool for EDF1

Discover related pathways, diseases and genes to EDF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.