Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, Mycoplasma
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC, ICC/IF
Host: Mouse Monoclonal
Species: Pm
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
E6AP was originally identified as the ubiquitin-protein ligase involved in human papillomavirus E6-mediated p53 degradation. It has since been shown to act as an E3 ubiquitin-protein ligase catalyzing the ubiquitination of several other protein substrates. Ubiquitin E3 ligases are overexpressed in many human cancers and their inhibition leads to growth suppression or apoptosis.
Bioinformatics
| Entrez |
Human
Mouse
|
| Uniprot |
Human
|
| Product By Gene ID |
7337 |
| Alternate Names |
- ANCR
- ANCREPVE6AP
- AS
- CTCL tumor antigen se37-2
- E6AP ubiquitin-protein ligase
- E6AP
- E6-AP
- EC 6.3.2.-
- EPVE6AP
- FLJ26981
- HPVE6A
- human papilloma virus E6-associated protein
- Human papillomavirus E6-associated protein
- Oncogenic protein-associated protein E6-AP
- Renal carcinoma antigen NY-REN-54
- UBE3A
- ubiquitin protein ligase E3A
- ubiquitin-protein ligase E3A
|
