E6AP/UBE3A Products

Antibodies
E6AP/UBE3A Antibody
E6AP/UBE3A Antibody
NB500-240
Species: Hu, Mu, Po, Ch, Fi, GP, Mk, Pm, Rb, Tr, Xp
Applications: WB, IP
Host: Rabbit Polyclonal
E6AP/UBE3A Antibody (2F6)
E6AP/UBE3A Antibody (2F6)
H00007337-M01
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF, IHC-P
Host: Mouse Monoclonal
E6AP/UBE3A Antibody
E6AP/UBE3A Antibody
NBP1-89092
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
E6AP/UBE3A Overexpression Lys ...
E6AP/UBE3A Overexpression Lysate (...
NBL1-17551
Applications: WB
Proteins
Recombinant Human E6AP/UBE3A ...
Recombinant Human E6AP/UBE3A Protein
H00007337-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human E6AP/UBE3A ...
Recombinant Human E6AP/UBE3A Protein
H00007337-P01
Species: Hu
Applications: WB, ELISA, PA
E6AP/UBE3A Recombinant Protei ...
E6AP/UBE3A Recombinant Protein Ant...
NBP2-38463PEP
Species: Hu
Applications: AC
RNAi
E6AP/UBE3A RNAi
E6AP/UBE3A RNAi
H00007337-R03
Species: Hu
Applications: RNAi, RNAi SP
E6AP/UBE3A RNAi
E6AP/UBE3A RNAi
H00007337-R02
Species: Hu
Applications: RNAi, RNAi SP
E6AP/UBE3A RNAi
E6AP/UBE3A RNAi
H00007337-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

UBE3A encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 7337
Alternate Names
  • EC 6.3.2.-
  • Oncogenic protein-associated protein E6-AP
  • E6AP
  • Human papillomavirus E6-associated protein
  • ubiquitin-protein ligase E3A
  • human papilloma virus E6-associated protein
  • CTCL tumor antigen se37-2
  • FLJ26981
  • E6AP ubiquitin-protein ligase
  • E6-AP
  • HPVE6A
  • AS
  • ANCREPVE6AP
  • Renal carcinoma antigen NY-REN-54
  • ubiquitin protein ligase E3A

Research Areas for E6AP/UBE3A

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Transcription Factors and Regulators

Bioinformatics Tool for E6AP/UBE3A

Discover related pathways, diseases and genes to E6AP/UBE3A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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