Dynein heavy chain Products

Description

Dynein heavy chain 9, axonemal is a protein that has three isoforms, with lengths of 4486, 4410, and 798 amino acids and weights of approximately 512, 503, and 798 kDa respectively. Dynein heavy chain generates force at the minus end of the microtubules that make up cilia which occurs due to the use of ADP that dynein obtains through ATPase activity. Current research is being done on diseases and disorders linked to this protein including ciliary dyskinesia, Kartagener syndrome, bronchiectasis, and malaria. Dynein heavy chain has also been shown to have interactions with BCL6, DNAH1, DNAH17, DNAH2, and DNAH3 in pathways such as the cytoplasmic microtubules pathway.

Bioinformatics

Entrez	1770 Human
Uniprot	Q9NYC9 Human
Product By Gene ID	1770
Alternate Names	axonemal, heavy polypeptide 9 ciliary dynein heavy chain 9 DNAH9 variant protein DYH9 dynein heavy chain 9, axonemal dynein, axonemal, heavy chain 9 HL20