DYNC1H1 Products

Antibodies
DYNC1H1 Antibody
DYNC1H1 Antibody
NBP1-84254
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DYNC1H1 Antibody
DYNC1H1 Antibody
H00001778-D01P
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
DYNC1H1 Antibody
DYNC1H1 Antibody
NBP1-47211
Species: Hu
Applications: PEP-ELISA
Host: Goat Polyclonal
Lysates
DYNC1H1 Overexpression Lysate ...
DYNC1H1 Overexpression Lysate (Den...
H00001778-T03
Applications: WB
Proteins
DYNC1H1 Partial Recombinant P ...
DYNC1H1 Partial Recombinant Protein
H00001778-Q01
Species: Hu
Applications: WB, ELISA, PA
DYNC1H1 Recombinant Protein
DYNC1H1 Recombinant Protein
H00001778-P01
Species: Hu
Applications: WB, ELISA, PA
DYNC1H1 Recombinant Protein A ...
DYNC1H1 Recombinant Protein Antigen
NBP1-84254PEP
Species: Hu
Applications: AC
RNAi
DYNC1H1 RNAi
DYNC1H1 RNAi
H00001778-R01
Species: Hu

Description

The DYNC1H1 gene encodes a cytoplasmic dynein 1 heavy chain 1 protein that is 4,646 amino acids long at 532 kDA. Dyneines function as molecular motors that contain ATPase activity. Defects in DYNC1H1 cause Charcot-Marie-Tooth Disease type 2O (CMT2O), mental retardation autosomal dominant type 13 (MRD13), as well as spinal muscular atrophy, lower extremity, autosomal dominant (SMALED). DYNC1H1 has also been investigated by researchers in myeloma, neuropathy, ciliary dyskinesia, lateral sclerosis, intellectual disabilities, lissencephaly, schizophrenia, malaria, and neurodegeneration. DYNC1H1 participates in centrosome maturation, adaptive immune system, cytoplasmic microtubules, cell cycle spindle assembly and chromosome separation, as well as phagosome and vasopressin-regulated water reabsorption. DYNC1H1 interacts with genes HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H43.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 1778
Alternate Names
  • cytoplasmic dynein 1 heavy chain 1
  • p22
  • DKFZp686P2245
  • dynein, cytoplasmic, heavy polypeptide 1
  • DHC1a
  • HL-3
  • KIAA0325
  • Dnchc1
  • DNECLDYHC
  • DNCLDNCH1
  • DHC1Dynein heavy chain, cytosolic
  • Cytoplasmic dynein heavy chain 1
  • dynein, cytoplasmic 1, heavy chain 1

Pathways for DYNC1H1

View related products by pathway and learn more about each of the pathways below.

Transport
Pathogenesis
Intracellular Transport
Synapse Assembly
Intraflagellar Transport
Proprioception
Localization
Reflex
Myelination

Research Areas for DYNC1H1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for DYNC1H1

Learn more about PTMs related to DYNC1H1.

Phosphorylation

Bioinformatics Tool for DYNC1H1

Discover related pathways, diseases and genes to DYNC1H1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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