Dynamin 2 Products

Description

The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin 1 is expressed exclusively in neurons, Dynamin 2 is ubiquitously expressed, and Dynamin 3 is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.

Bioinformatics

Entrez	1785 Human 25751 Rat
Uniprot	AAH54501 Human NP_001005360.1 Human NP_004936 Human P50570 Human
Product By Gene ID	1785
Alternate Names	CMTDI1CMT2M CMTDIBdynamin II DI-CMTB DYN2EC 3.6.5.5 dynamin 2 dynamin-2 DYNII

Research Areas for Dynamin 2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Membrane Trafficking and Chaperones
Neuronal Cell Markers
Neuroscience

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EEA1 Antibodies in Endosomal Transport and Signalling Studies EEA1, or Early Endosome Antigen 1, is a phospholipid-binding protein essential for endosomal membrane trafficking and fusion, and is a useful endosomal marker. We at Novus Biologicals have an extensive EEA1 antibody catalog, with antibodies that have ...    Read more.

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