Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylationand inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved insynthesis of diphthamide in EEF2 (Liu et al., 2004 (PubMed 15485916)).(supplied by OMIM)
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human Human |
| Product By Gene ID |
120526 |
| Alternate Names |
- CSL-type zinc finger-containing protein 3
- DnaJ (Hsp40) homolog, subfamily C, member 24
- dnaJ homolog subfamily C member 24
- DPH4 homolog
- DPH4, JJJ3 homolog (S. cerevisiae)
- DPH4, JJJ3 homolog
- DPH41700030A21Rik
- JJJ3
- S. cerevisiae)
- ZCSL3
- zinc finger, CSL domain containing 3
- zinc finger, CSL-type containing 3
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