DNMT1 Products

Antibodies
DNMT1 Antibody
DNMT1 Antibody
NB100-264
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
DNMT1 Antibody
DNMT1 Antibody
Species: Hu, Mu
Applications: WB, IP, PLA
Host: Rabbit Polyclonal
Kits
DNMT1 Assay/Inhibitor Screeni ...
DNMT1 Assay/Inhibitor Screening As...
KA1604
Applications: Func
DNMT1 Fluorometric Assay Kit
DNMT1 Fluorometric Assay Kit
KA1516
Applications: Func
DNMT1 Assay/Inhibitor Screeni ...
DNMT1 Assay/Inhibitor Screening As...
KA1515
Applications: Func
Proteins
Recombinant Human DNMT1 Prote ...
Recombinant Human DNMT1 Protein
H00001786-Q01
Species: Hu
Applications: WB, ELISA, PA
DNMT1 Recombinant Protein Ant ...
DNMT1 Recombinant Protein Antigen
NBP1-84328PEP
Species: Hu
Applications: AC
RNAi
DNMT1 RNAi
DNMT1 RNAi
H00001786-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

DNA (cytosine-5)-methyltransferase 1 (DNMT1) plays a role in the regulation of tissue-specific cytosine residue methylation patterns that are established during development. Spec ifically, DNMT-1 interacts with Histone deacetylases and other methyltransferases to preferentially methylate hemimethylated DNA in coordination with the methylation of histones.

Improper methylation patterns have been linked to certain human tumors and developmental abnormalities. DNMT1 antibodies are useful tools for DNA methlyation research and studies on certian cancer.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 1786
Alternate Names
  • EC 2.1.1.37
  • M.HsaI
  • DNA MTase HsaI
  • Dnmt1
  • DNA methyltransferase HsaI
  • m.HsaI
  • CXXC-type zinc finger protein 9
  • DNA methyltransferase 1
  • DNMT
  • DNA (cytosine-5)-methyltransferase 1
  • AIM
  • CXXC9CXXC finger protein 9
  • MCMTMGC104992
  • FLJ16293
  • DNA (cytosine-5-)-methyltransferase 1

Research Areas for DNMT1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Chromatin Modifiers
Chromatin Research
Core ESC-Like Genes
DNA Methyltransferases
Epigenetics
Phospho-Specific
Stem Cell Markers
Transcription Factors and Regulators

Bioinformatics Tool for DNMT1

Discover related pathways, diseases and genes to DNMT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related DNMT1 Blog Posts

Check out the latest blog posts on DNMT1.
The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies
Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...    Read more.
The role of DNMT3A in development
Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...    Read more.
Controlling Epigenetic Signaling with Dnmt1 and Dnmt3b
Dnmt1 belongs to the C5-methyltransferase family that repairs cytosines in dsDNA using a nucleophilic attack mechanism. Dnmt1 is the most abundant mammalian DNA methyltransferase. It is the key methylation maintenance enzyme for both DNA replication/r...    Read more.
PCNA Antibodies: Marking Cell Proliferation & DNA Replication
Proliferating Cell Nuclear Antigen (PCNA), also known as the polymerase delta auxiliary protein, is a nuclear protein essential for DNA replication as well as DNA excision and mismatch repair pathways. It has a large role in cell cycle regulation and...    Read more.
DNMT's: An Overview of 3 DNA Methyltransferases
DNA methyltransferases catalyze the transfer of the methyl group from S-andenosyl methionine (SAM) to DNA. Such methylation has wide ranging function in the cell, including organismal development and cell differentiation. In cancer, abnormal hypermeth...    Read more.
Read more DNMT1 related blogs.