DMTF1 Products

Antibodies
DMTF1 Antibody (5C6)
DMTF1 Antibody (5C6)
H00009988-M03
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
DMTF1 Antibody
DMTF1 Antibody
NBP1-84073
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DMTF1 Antibody
DMTF1 Antibody
NBP2-26208
Species: Hu, Mu, Rt
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Proteins
Recombinant Human DMTF1 Prote ...
Recombinant Human DMTF1 Protein
H00009988-Q01
Species: Hu
Applications: WB, ELISA, PA
DMTF1 Recombinant Protein Ant ...
DMTF1 Recombinant Protein Antigen
NBP1-84073PEP
Species: Hu
Applications: AC
RNAi
DMTF1 RNAi
DMTF1 RNAi
H00009988-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

DMTF1 encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 9988
Alternate Names
  • FLJ25188
  • cyclin-D-binding Myb-like transcription factor 1
  • hDMTF1
  • cyclin D-binding Myb-like protein 1
  • Cyclin-D-interacting Myb-like protein 1
  • hDMP1DMTF
  • DMP1FLJ76054
  • FLJ41265
  • cyclin D binding myb-like transcription factor 1

Research Areas for DMTF1

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer

PTMs for DMTF1

Learn more about PTMs related to DMTF1.

Phosphorylation
Methylation
Ubiquitination

Bioinformatics Tool for DMTF1

Discover related pathways, diseases and genes to DMTF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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