DHX38 Products

Description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process.

Bioinformatics

Entrez	9785 Human 64340 Mouse
Uniprot	Q92620 Human
Product By Gene ID	9785
Alternate Names	ATP-dependent RNA helicase DHX38 DDX38pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 DEAH box protein 38 EC 3.6.1 EC 3.6.4.13 KIAA0224pre-mRNA splicing factor ATP-dependent RNA helicase PRP16 PRP16 homolog of S.cerevisiae PRP16hPrp16 PRPF16