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VC001). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to keratinocyte membranes. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank">
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. Desmoglein 1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
![Immunohistochemistry Desmoglein-1 Antibody [Unconjugated] - Propeptide](http://images.novusbio.com/images/antibody/Desmoglein-1_AF944_Immunohistochemistry_9801.jpg)
![Immunohistochemistry Desmoglein-1 Antibody (129204) [Unconjugated]](http://images.novusbio.com/images/antibody/Desmoglein1_MAB944_Immunohistochemistry_20618.jpg)
