Defensin alpha 4 Products

Description

Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. The cryptidin-4 gene is unique among the Paneth cell alpha defensins in that it is inactive in the duodenum, but expressed at maximal levels in the distal small bowel.

Bioinformatics

Entrez	1669 Human
Product By Gene ID	1669
Alternate Names	corticostatin DEF4 defensin, alpha 4, corticostatin defensin, alpha 4, preproprotein HNP-4 HP4 HP-4 MGC120099 MGC138296 neutrophil defensin 4