DDR2 Products

Antibodies
DDR2 Antibody [Unconjugated]
DDR2 Antibody [Unconjugated]
AF2538
Species: Hu
Applications: WB, Simple Western, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
DDR2 Antibody (290814)
DDR2 Antibody (290814)
MAB2538
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
DDR2 [p Tyr740] Antibody (111 ...
DDR2 [p Tyr740] Antibody (1119D) [...
MAB25382
Species: Hu
Applications: WB, Simple Western
Host: Rabbit Monoclonal
Lysates
DDR2 Overexpression Lysate (N ...
DDR2 Overexpression Lysate (Native)
NBL1-09778
Applications: WB
DDR2 Overexpression Lysate (N ...
DDR2 Overexpression Lysate (Native)
NBP2-09152
Applications: WB
DDR2 Overexpression Lysate (N ...
DDR2 Overexpression Lysate (Native)
NBP2-08744
Applications: WB
Proteins
DDR2 Recombinant Protein Anti ...
DDR2 Recombinant Protein Antigen
NBP2-56485PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human DDR2 Protei ...
Recombinant Human DDR2 Protein
NBP2-52357
Species: Hu
Applications: PAGE
Recombinant DDR2 Protein
Recombinant DDR2 Protein
NBP1-99508
RNAi
DDR2 RNAi
DDR2 RNAi
H00004921-R08
Species: Hu
Applications: RNAi, RNAi SP
DDR2 RNAi
DDR2 RNAi
H00004921-R07
Species: Hu
Applications: RNAi, RNAi SP

Description

DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/ threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 4921
Alternate Names
  • EC 2.7.10
  • CD167 antigen-like family member B
  • CD167b antigen
  • TYRO10
  • tyrosylprotein kinase
  • Tyrosine-protein kinase TYRO10
  • neurotrophic tyrosine kinase receptor related 3
  • Receptor protein-tyrosine kinase TKT
  • migration-inducing gene 16 protein
  • Neurotrophic tyrosine kinase, receptor-related 3
  • hydroxyaryl-protein kinase
  • Discoidin domain receptor 2
  • discoidin domain-containing receptor 2
  • discoidin domain receptor family, member 2
  • NTRKR3cell migration-inducing protein 20
  • TKTMIG20a
  • EC 2.7.10.1
  • discoidin domain receptor tyrosine kinase 2

PTMs for DDR2

Learn more about PTMs related to DDR2.

Phosphorylation
Glycosylation
Cleavage
Methylation

Bioinformatics Tool for DDR2

Discover related pathways, diseases and genes to DDR2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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