DDR1 Products

Antibodies
DDR1 Antibody [Unconjugated]
DDR1 Antibody [Unconjugated]
AF2396
Species: Hu
Applications: WB, Simple Western, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
DDR1 Antibody
DDR1 Antibody
NBP1-33134
Species: Hu, Mu, Rt, Po, Bv, Mk, Pm
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
DDR1 Antibody (2G4E12)
DDR1 Antibody (2G4E12)
NBP1-28861
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
DDR1 Overexpression Lysate (D ...
DDR1 Overexpression Lysate (Denatu...
H00000780-T01
Species: Hu
Applications: WB
DDR1 Overexpression Lysate (N ...
DDR1 Overexpression Lysate (Native)
NBP2-09858
Applications: WB
DDR1 Overexpression Lysate (N ...
DDR1 Overexpression Lysate (Native)
NBP2-09857
Applications: WB
Proteins
Recombinant Human DDR1 Protei ...
Recombinant Human DDR1 Protein
H00000780-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human DDR1 Protei ...
Recombinant Human DDR1 Protein
H00000780-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human DDR1 Protei ...
Recombinant Human DDR1 Protein
NBP2-60221
Species: Hu
Applications: PAGE
RNAi
DDR1 RNAi
DDR1 RNAi
H00000780-R04
Species: Hu
Applications: RNAi, RNAi SP
DDR1 RNAi
DDR1 RNAi
H00000780-R05
Species: Hu
Applications: RNAi, RNAi SP
DDR1 RNAi
DDR1 RNAi
H00000780-R08
Species: Hu
Applications: RNAi, RNAi SP

Description

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 780
Alternate Names
  • EC 2.7.10
  • MCK10
  • ENTRK4
  • DDR
  • TRK E
  • discoidin domain receptor family, member 1
  • Protein-tyrosine kinase 3A
  • EC 2.7.10.1
  • Epithelial discoidin domain receptor 1
  • CD167 antigen-like family member A
  • Discoidin receptor tyrosine kinase
  • PTK3A
  • CD167a antigen
  • NTRK4
  • MCK-10
  • HGK2
  • PTK3A protein tyrosine kinase 3A
  • EDDR1
  • receptor, type 4
  • discoidin domain receptor tyrosine kinase 1

PTMs for DDR1

Learn more about PTMs related to DDR1.

Phosphorylation
Cleavage
Biotinylation
Glycosylation
Methylation
Dephosphorylation

Bioinformatics Tool for DDR1

Discover related pathways, diseases and genes to DDR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related DDR1 Blog Posts

Check out the latest blog posts on DDR1.
Further unraveling the role of gamma H2AX in DNA damage response
Our genome experiences a moderate amount of DNA damage in our cells on a daily basis.  This DNA damage can be in response to external environmental factors, or be a result of our internal metabolic processes going awry.  While normal rates of DNA ...    Read more.
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