DC8 Products

Description

DC8 encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. It is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez	25936 Human
Uniprot	AAH07067.1 Human NP_056286 Human
Product By Gene ID	25936
Alternate Names	C1orf48 chromosome 1 open reading frame 48 DC8 DKFZp566O1646 DKFZP566O1646 kinetochore-associated protein NSL1 homolog MIS14 NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

Research Areas for DC8

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DNA Repair