DAD1 Products

Antibodies
DAD1 Antibody
DAD1 Antibody
NBP1-77197
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IF
Host: Rabbit Polyclonal
DAD1 Antibody
DAD1 Antibody
NB600-669
Species: Hu, Mu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
DAD1 Antibody
DAD1 Antibody
NBP1-02946
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
Recombinant Human DAD1 Protei ...
Recombinant Human DAD1 Protein
H00001603-P01
Species: Hu
Applications: WB, ELISA, PA
DAD1 Recombinant Protein Anti ...
DAD1 Recombinant Protein Antigen
NBP1-82466PEP
Species: Hu
Applications: AC
DAD1 Peptide
DAD1 Peptide
NBP1-77197PEP
Species: Hu
Applications: AC
RNAi
DAD1 RNAi
DAD1 RNAi
H00001603-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Defender of cell death 1 (DAD1) was initially discovered in BHK21 cells as a negative regulator of programmed cell death, a process important for normal organism development and tissue homeostasis. DAD1 was later shown to be a subunit of the mammalian oligosaccharyltransferase complex and is required for its function and structural integrity. Mice lacking DAD1 express abnormal N-linked glycoproteins and undergo increased apoptotic-associated embryonic death. Furthermore, overexpression of DAD1 mRNA is seen in some human hepatocellular carcinomas, indicating it may also play a role in carcinogenesis. It should be noted that DAD1 is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 1603
Alternate Names
  • DAD-1
  • oligosaccharyltransferase 2 homolog
  • Oligosaccharyl transferase subunit DAD1
  • dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
  • OST2
  • defender against cell death 1EC 2.4.1.119

Research Areas for DAD1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer

PTMs for DAD1

Learn more about PTMs related to DAD1.

Glycosylation
Cleavage
Phosphorylation

Bioinformatics Tool for DAD1

Discover related pathways, diseases and genes to DAD1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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