Species: Hu, Mu, Rt, Bv, Ca, Eq
Host: Rabbit Polyclonal
WB, ELISA, PLAHost:
Applications: WB, ELISA, PA, AP
Applications: RNAi, RNAi SP
Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
|Product By Gene ID
- dishevelled-associated activator of morphogenesis 1
- disheveled-associated activator of morphogenesis 1
- dishevelled associated activator of morphogenesis 1
Bioinformatics Tool for DAAM1
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