DAAM1 Products

Description

Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.

Bioinformatics

Entrez	23002 Human
Uniprot	NP_055807 Human
Product By Gene ID	23002
Alternate Names	disheveled-associated activator of morphogenesis 1 dishevelled associated activator of morphogenesis 1 dishevelled-associated activator of morphogenesis 1 KIAA0666FLJ41657

Research Areas for DAAM1

Find related products by research area and learn more about each of the different research areas below.

Growth and Development
Neuronal Cell Markers
Wnt Signaling Pathway