Cytokeratin 6a Products

Antibodies
Cytokeratin 6a Antibody
Cytokeratin 6a Antibody
NBP1-31443
Species: Hu, Mu, Bovine
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Cytokeratin 6a Antibody
Cytokeratin 6a Antibody
NBP2-49325
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Cytokeratin 6a Antibody
Cytokeratin 6a Antibody
NBP1-98557
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
Cytokeratin 6a Overexpression ...
Cytokeratin 6a Overexpression Lysa...
NBL1-12394
Applications: WB
Proteins
Cytokeratin 6a Recombinant Pr ...
Cytokeratin 6a Recombinant Protein
H00003853-P01
Species: Hu
Applications: WB, ELISA, PA
Cytokeratin 6a Recombinant Pr ...
Cytokeratin 6a Recombinant Protein
H00003853-P02
Species: Hu
Applications: WB, ELISA, PA
Cytokeratin 6a Recombinant Pr ...
Cytokeratin 6a Recombinant Protein...
NBP2-49325PEP
Species: Hu
Applications: AC

Description

The human type II Cytokeratin 6 (CK6; 56 kDa) is expressed in a heterogeneous array of epithelial tissues under normal conditions, but is better known for its strong induction in stratified epithelia that feature an enhanced cell proliferation rate or abnormal differentiation. It has been demonstrated that CK6 isoform, CK6a, is clearly the dominant CK6 isoform in skin tissue samples and cultured epithelial cell lines and that the various isoforms are differentially regulated within and between epithelial tissue types (1). The murine genome is known to have two keratin 6 (CK6) genes, mouse CK6, CK6a and MK6b. These genes display a complex expression pattern with constitutive expression in the epithelia of oral mucosa, hair follicles, and nail beds (2). Pachyonychia congenital (PC) is characterized by hypertrophic nail dystrophy and associated ectodermal features. PC-1 subtype is associated with mutations in keratins 6a or 16, whereas PC-2 subtype is linked to mutations in keratins 6b or 17 (3).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 3853
Alternate Names
  • KRT6C
  • Allergen Hom s 5
  • CK6A
  • Keratin-6A
  • keratin 6D
  • Cytokeratin-6D
  • keratin 6C
  • Cytokeratin-6A
  • KRT6D
  • CK-6D
  • K6A
  • CK-6A
  • Type-II keratin Kb6
  • keratin, type II cytoskeletal 6A
  • K6D
  • keratin, epidermal type II, K6A
  • K6C
  • cytokeratin 6D
  • CK6D
  • cytokeratin 6C
  • CK6C
  • cytokeratin 6A
  • keratin 6A

Research Areas for Cytokeratin 6a

Find related products by research area and learn more about each of the different research areas below.

Cytoskeleton Markers
Stem Cell Markers

PTMs for Cytokeratin 6a

Learn more about PTMs related to Cytokeratin 6a.

Phosphorylation

Bioinformatics Tool for Cytokeratin 6a

Discover related pathways, diseases and genes to Cytokeratin 6a. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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