Cystatin S Products

Description

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function. [provided by RefSeq]

Bioinformatics

Entrez	1472 Human
Uniprot	NM_001899 Human NP_001890.1 Human P01036 Human
Product By Gene ID	1472
Alternate Names	cystatin 4 cystatin S Cystatin-4 cystatin-4 cystatin-S cystatin-SA-III Cystatin-SA-III MGC71923 Salivary acidic protein 1