CXCL12/SDF-1 beta Products

Description

For background information on chemokines, see CXCL11 (SCYB11; MIM 604852). Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF (see MIM 191160), or IL1 (see MIM 147760). The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.[supplied by OMIM]

Bioinformatics

Entrez	6387 Human
Uniprot	P48061
Product By Gene ID	6387
Alternate Names	CXCL12/SDF-1 beta hSDF-1beta SDF 1beta SDF1 beta SDF1b

Research Areas for CXCL12/SDF-1 beta

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Biologically Active Proteins