Hu, Mu, Rt, Bv, Ca, Ch, Fe, Pm, RbApplications:
WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-PHost:
Hu, Mouse, RatApplications:
Applications: WB, ELISA
Host: Mouse Monoclonal
Applications: B/N, Ctrl
Retinoic acid (RA), a metabolite of vitamin A, plays an important role in growth and differentiation by modulation of expression of certain genes. RA functions through its interaction with the nuclear protein, retinoic acid receptor (RAR) and the 9-cis RA with retinoid X receptor (RXR). The Cellular Retinoic Acid Binding Proteins (CRABP) bind RA with a high affinity and belong to the family of fatty acid binding proteins. Two forms of CRABP have been characterized, CRABP 1 and CRABP 2 which share ~75% sequence conservation. The main role of CRABP 1 may be to protect retinoids from non-specific dehydrogenases and direct them to specific enzymes. The precise role of CRABP 2 is still poorly understood but it seems to play a role in the interaction of ligands (RA, 9-cis RA) with nuclear receptors (RAR/RXR).
|Product By Gene ID
- RBP5Cellular retinoic acid-binding protein I
- CRABP-Icellular retinoic acid-binding protein 1
- cellular retinoic acid binding protein 1
Research Areas for CRABP1
Find related products by research area and learn more about each of the different research areas below.Stem Cell Markers
Bioinformatics Tool for CRABP1
Discover related pathways, diseases and genes to CRABP1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.