CORO2A Products

Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq]. Transcript Variant: This variant (2) contains a distinct 5' UTR transcribed from an alternate exon, as compared to variant 1. Variants 1 and 2 encode the same protein and contain the same 3' UTR. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments.

Bioinformatics

Product By Gene ID	7464
Alternate Names	CLIPINB coronin, actin binding protein, 2A coronin, actin-binding protein, 2A coronin-like protein B DKFZp686G19226 IR10coronin 2A WD protein IR10 WD repeat-containing protein 2 WDR2coronin-2A WD-repeat protein 2

Research Areas for CORO2A

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Signal Transduction