COP Products

Description

Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of theproteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release ofIL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokineresponse. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, andstaurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspasesCASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2

Bioinformatics

Product By Gene ID	114769
Alternate Names	CARD only domain-containing protein 1 CARD only protein caspase recruitment domain family, member 16 Caspase-1 inhibitor COP COP1caspase-1 dominant-negative inhibitor pseudo-ICE COPcaspase recruitment domain-containing protein 16 EC 3.4.22.36 Pseudo interleukin-1 beta converting enzyme pseudo interleukin-1beta converting enzyme Pseudo-ICE

Research Areas for COP

Find related products by research area and learn more about each of the different research areas below.

Apoptosis