COP Products

Antibodies
COP Antibody
COP Antibody
H00114769-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
COP Antibody
COP Antibody
NBP2-30778
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
COP Antibody
COP Antibody
H00114769-D01P
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Lysates
COP Overexpression Lysate (De ...
COP Overexpression Lysate (Denatured)
H00114769-T01
Species: Hu
Applications: WB
COP Overexpression Lysate (Na ...
COP Overexpression Lysate (Native)
NBL1-09376
Applications: WB
COP Overexpression Lysate (Na ...
COP Overexpression Lysate (Native)
NBP2-11021
Applications: WB
Proteins
COP Partial Recombinant Prote ...
COP Partial Recombinant Protein
H00114769-Q01
Species: Hu
Applications: WB, ELISA, PA
COP Recombinant Protein
COP Recombinant Protein
H00114769-P01
Species: Hu
Applications: WB, ELISA, PA
COP Recombinant Protein Antig ...
COP Recombinant Protein Antigen
NBP2-30778PEP
Species: Hu
Applications: AC
RNAi
COP RNAi
COP RNAi
H00114769-R01
Species: Hu
COP RNAi
COP RNAi
H00114769-R02
Species: Hu

Description

Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of theproteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release ofIL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokineresponse. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, andstaurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspasesCASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 114769
Alternate Names
  • CARD only domain-containing protein 1
  • EC 3.4.22.36
  • Pseudo interleukin-1 beta converting enzyme
  • Pseudo-ICE
  • Caspase-1 inhibitor COP
  • pseudo interleukin-1beta converting enzyme
  • PSEUDO-ICE
  • COP1caspase-1 dominant-negative inhibitor pseudo-ICE
  • COPcaspase recruitment domain-containing protein 16
  • CARD only protein
  • caspase recruitment domain family, member 16

Research Areas for COP

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

Bioinformatics Tool for COP

Discover related pathways, diseases and genes to COP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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