Connexin 50/GJA8 Products

Antibodies
Connexin 50/GJA8 Antibody
Connexin 50/GJA8 Antibody
NBP1-52143
Species: Hu, Mu, Rt, Bv, Ca
Applications: PEP-ELISA
Host: Goat Polyclonal
Connexin 50/GJA8 Antibody
Connexin 50/GJA8 Antibody
NBP1-59201
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Connexin 50/GJA8 Antibody (8A ...
Connexin 50/GJA8 Antibody (8A10)
H00002703-M02-100ug
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
Connexin 50/GJA8 Overexpressi ...
Connexin 50/GJA8 Overexpression Ly...
NBP2-07766
Applications: WB
Proteins
Connexin 50/GJA8 Recombinant ...
Connexin 50/GJA8 Recombinant Protein
H00002703-P01
Species: Hu
Applications: WB, ELISA, PA
Connexin 50/GJA8 Partial Reco ...
Connexin 50/GJA8 Partial Recombina...
H00002703-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Connexin 50/GJA8 RNAi
Connexin 50/GJA8 RNAi
H00002703-R01
Species: Hu

Description

The 433 amino acid long, 48 kDA transmembrane connexin, gap junction alpha-8 protein encoded by the GJA8 gene is critical in growth and development of lens fiber cells. Mutations in the GJA8 gene may lead to zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. The GJA8 gene has been linked to myopia, microphthalmia, neuronitis, cycstic fibrosis, neuopathy, cervical adenocarcinoma, and juvenile myoclonic epilepsy. The GJA8 gene interacts with TJP1, MIP, MED14, GJA1, and GJB1 to participate in pathways such as gap junction assembly, membrane trafficking, and connexin synthesis.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 2703
Alternate Names
  • Cx50
  • MP70
  • Connexin-50
  • CZP1
  • lens intrinsic membrane protein MP70
  • CAE
  • gap junction membrane channel protein alpha-8
  • gap junction protein, alpha 8, 50kDa (connexin 50)
  • gap junction alpha-8 protein
  • alpha 8, 50kD (connexin 50)
  • gap junction protein, alpha 8, 50kDa

Pathways for Connexin 50/GJA8

View related products by pathway and learn more about each of the pathways below.

Transport
Eye Development
Cell Adhesion
Translation
Cell Death
Cell Differentiation
Cell Growth
Virulence
Pathogenesis
Localization
Cell Maturation

PTMs for Connexin 50/GJA8

Learn more about PTMs related to Connexin 50/GJA8.

Phosphorylation

Bioinformatics Tool for Connexin 50/GJA8

Discover related pathways, diseases and genes to Connexin 50/GJA8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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