Common beta Chain Products

Antibodies
Common beta Chain Antibody
Common beta Chain Antibody
AF906
Species: Hu
Applications: WB, Flow
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Common beta Chain Antibody (4 ...
Common beta Chain Antibody (4H3)
NBP2-46365
Species: Hu
Applications: WB, IHC, IHC-P
Host: Mouse Monoclonal
Common beta Chain Antibody
Common beta Chain Antibody
NBP1-61309
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Common beta Chain Overexpress ...
Common beta Chain Overexpression L...
H00001439-T01
Applications: WB
Proteins
Common beta Chain Recombinant ...
Common beta Chain Recombinant Protein
NBP2-52244
Species: Hu
Applications: PAGE
Common beta Chain Recombinant ...
Common beta Chain Recombinant Protein
NBC1-18483
Species: Mu
Applications: PAGE
RNAi
Common beta Chain RNAi
Common beta Chain RNAi
H00001439-R02
Species: Hu

Description

Interleukin-3 receptor (IL-3R) is a heterodimer cytokine composed of alpha chain and beta chain. IL-3R beta subunit (CD131, beta C) is a common shared beta chain of the receptor for granulocyte- macrophage colony-stimulating factor (GM-CSF) and IL-5 (1). While the beta chain can not bind to the ligand alone, but it is essential for high affinity ligand binding (2). The cytoplasmic portion of the beta chain contains the major domains necessary for ligand-induced proliferation (3). IL-3R beta is expressed in neutrophil, eosinophil, monocyte, and hematpoietic stem cells. A point mutation leading to defective IL-3R beta expression has been associated to Human pulmonary alveolar proteinosis (PAP), a rare cause of respiratory failure (4).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Mouse
Product By Gene ID 1439
Alternate Names
  • CD131 antigen
  • GM-CSF/IL-3/IL-5 receptor common beta subunit
  • interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3receptor, beta (high affinity)
  • IL3RB
  • GM-CSF/IL-3/IL-5 receptor common beta-chain
  • CDw131
  • cytokine receptor common subunit beta
  • CD131
  • beta, low-affinity
  • colony stimulating factor 2 receptor, beta, low-affinity(granulocyte-macrophage)

Research Areas for Common beta Chain

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Phospho-Specific

PTMs for Common beta Chain

Learn more about PTMs related to Common beta Chain.

Phosphorylation
Ubiquitination

Bioinformatics Tool for Common beta Chain

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