Applications: WB, IHC
Host: Mouse monoclonal
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: WB, ELISA, PA
Applications: WB, ELISA
Circadian Locomotor Output Cycles Kaput (CLOCK) is a bHLH/PAS protein that plays an important role in the molecular clock mechanism. Specifically, CLOCK activates the central circadian loop by stimulating expression of Period and Timeless proteins. CLOCK has also been shown to interact strongly with other bHLH-PAS proteins such as MOP3, a BMAL1 isoform.
CLOCK levels peak during the late night and the early part of the subjective day. Mutations in CLOCK causes defective transcriptional activity and lengthens the circadian period, leading to abnormal circadian behavior.
CLOCK antibodies are useful tools for research on circadian rythmns, sleep biology and hormonal cycles.
|Product By Gene ID
- clock (mouse) homolog
- EC 188.8.131.52
- Class E basic helix-loop-helix protein 8
- circadian locomoter output cycles protein kaput
- KIAA0334bHLHe8circadian locomoter output cycles kaput protein
- clock homolog (mouse)
Bioinformatics Tool for CLOCK
Discover related pathways, diseases and genes to CLOCK. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.