CLCC1 Products

Description

Chloride channels (CLCs) regulate cellular traffic of chloride ions, a critical component of all living cells. CLCs are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. CLCC1 (Chloride channel CLIC-like protein 1), also known as MCLC (Mid-1-related chloride channel) or KIAA0761, is a 551 amino acid multi-pass membrane protein that belongs to the chloride channel MCLC family. CLCC1 is related to the Saccharomyces cerevisiaeprotein Mid-1 and is believed to function as an intracellular chloride channel that is expressed in lung, brain, muscle, liver and testis. Localizing to intracellular compartments such as the Golgi apparatus, the endoplasmic reticulum (ER) and the nuclear envelope, CLCC1 is expressed as four isoforms due to alternative splicing events, namely hMCLC-1, hMCLC-2, hMCLC-3 and hMCLC-4.

Bioinformatics

Entrez	23155 Human
Uniprot	NM_015127 Human NP_055942.1 Human Q96S66 Human
Product By Gene ID	23155
Alternate Names	chloride channel CLIC-like 1 KIAA0761 MCLCchloride channel CLIC-like protein 1 Mid-1-related chloride channel 1 Mid-1-related chloride channel protein 1 Mid1-related chloride channel