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VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in Goblet cells. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank">
Species: Hu Applications: Simple Western, IHC Host: Mouse Monoclonal
CLCA1 encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq]
![Immunohistochemistry CLCA1 Antibody (1022517) [Unconjugated]](http://images.novusbio.com/images/antibody/mab10766_human-clca1-mab-clone-1022517-immunohistochemistry-2052021143535.jpg)
![Simple Western CLCA1 Antibody (1022517) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab10766_human-clca1-mab-clone-1022517-simple-western-278202115192.jpg)
