Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP, Enzyme Activity
Species: Hu
Applications: AC
Description
The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. mRNA studies indicate that claudin-7 is specifically expressed in mouse lung and kidney, but not in heart, brain, spleen, liver, skeletal muscle or testis. The gene encoding human claudin-7 maps to chromosome 17p13.
Bioinformatics
| Entrez |
Human
Rat
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
1366 |
| Alternate Names |
- CEPTRL2
- claudin 7
- claudin-1
- claudin-7
- CLDN-7
- clostridium perfringens enterotoxin receptor-like 2
- CPETRL2
|
Research Areas for Claudin-7
Find related products by research area and learn more about each of the different research areas below.
Breast CancerCancer
