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Claudin-6 Products

Antibodies
Claudin-6 Antibody (342927) [ ...
Claudin-6 Antibody (342927) [Uncon...
MAB3656
F0101B). Quadrant markers were set based on Mouse IgG2B Isotype Control Antibody (Catalog # MAB0041). View our protocol for Staining Membrane-associated Proteins." class="big_lightbox" target="_blank"> Flow Cytometry Claudin-6 Antibody (342927) [Unconjugated]
SC019), using Mouse Anti-Human Claudin-6 Monoclonal Antibody (Catalog # MAB3656) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). SOX17 was also detected using Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (green; Catalog # AF1924). Specific staining of Claudin-6 was localized to cell surfaces. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry Claudin-6 Antibody (342927) [Unconjugated]
Applications: Flow, CyTOF-ready, ICC/IF
Host: Mouse Monoclonal
Claudin-6 Antibody (9H8) - BS ...
Claudin-6 Antibody (9H8) - BSA Free
NBP3-26651
Species: Hu, Pm-Cm
Applications: ELISA, Flow
Host: Human Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human Claudin-6 - Ready-To-U ...
Human Claudin-6 - Ready-To-Use EL...
NBP3-31253
Species: Hu
Applications: ELISA
Human Claudin-6 ELISA Kit (Co ...
Human Claudin-6 ELISA Kit (Colorim...
NBP3-27392
Species: Hu
Applications: ELISA
Lysates
Claudin-6 Overexpression Lysa ...
Claudin-6 Overexpression Lysate
NBL1-09248
Species: Hu
Applications: WB

Description

The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule. Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-6 is expressed in differentiated F9 cells that resemble tight junction-bearing viceral endoderm resulting from stimulation with retinoc acid and mediated by RXRalpha and RARgamma. Claudin-6 is absent in mouse brain and lung. The human claudin-6 gene maps to chromosome 16p13.3.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 9074
Alternate Names
  • claudin 6
  • claudin-6
  • Skullin
  • skullin

Research Areas for Claudin-6

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Markers