CIZ1 Products

Antibodies
CIZ1 Antibody
CIZ1 Antibody
NBP2-33890
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
CIZ1 Antibody
CIZ1 Antibody
NBP2-15906
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
CIZ1 Antibody
CIZ1 Antibody
NB100-74624
Species: Hu, Pm, RM
Applications: WB, IP
Host: Rabbit Polyclonal
Lysates
CIZ1 Overexpression Lysate (D ...
CIZ1 Overexpression Lysate (Denatu...
H00025792-T01
Species: Hu
Applications: WB
CIZ1 Overexpression Lysate (N ...
CIZ1 Overexpression Lysate (Native)
NBP2-09528
Applications: WB
CIZ1 Overexpression Lysate (N ...
CIZ1 Overexpression Lysate (Native)
NBP2-07489
Applications: WB
Proteins
Recombinant Human CIZ1 Protei ...
Recombinant Human CIZ1 Protein
H00025792-P01
Species: Hu
Applications: WB, ELISA, PA
CIZ1 Recombinant Protein Anti ...
CIZ1 Recombinant Protein Antigen
NBP2-33890PEP
Species: Hu
Applications: AC
RNAi
CIZ1 RNAi
CIZ1 RNAi
H00025792-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

CIZ1 (Cip1 interacting zinc-finger protein) was identified as a protein that associates with the cell-cycle inhibiting protein, p21 (Cip1/Waf1). CIZ1 is a member of the matrin 3 protein family and has been shown to bind DNA consensus sequences and co-localize with PCNA during replication. In breast cancer cells, CIZ1 was shown to associate with Cdk2 and dynein light chain 1 (DLC1), a cytoskeletal signaling protein involved in cell cycle regulation and tumorigenesis. Studies of the role of CIZ1 in breast tumorigenesis revealed that CIZ1 is an estrogen-responsive gene that functions as a coactivator of the estrogen receptor. Targeted depletion of CIZ1 inhibits entry into S-phase. This finding along with evidence that CIZ1 interacts with multiple cell cycle regulatory proteins and localizes to DNA replication foci, indicates that CIZ1 plays a critical role in the regulation of DNA replication.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 25792
Alternate Names
  • NP94
  • cip1-interacting zinc finger protein
  • Zinc finger protein 356
  • LSFR1ZNF356Nuclear protein NP94
  • CDKN1A-interacting zinc finger protein 1
  • CDKN1A interacting zinc finger protein 1

Research Areas for CIZ1

Find related products by research area and learn more about each of the different research areas below.

Cancer

PTMs for CIZ1

Learn more about PTMs related to CIZ1.

Phosphorylation

Bioinformatics Tool for CIZ1

Discover related pathways, diseases and genes to CIZ1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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