CIDEC Products

Description

DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumors, CIDE-3 may play an important role in prevention of tumorigenesis.

Bioinformatics

Entrez	14311 Mouse 63924 Human
Uniprot	AAH16851 Human NM_022094 Human NP_071377 Human NP_071377.2 Human Q96AQ7 Human
Product By Gene ID	63924
Alternate Names	cell death activator CIDE-3 cell death-inducing DFFA-like effector c Cell death-inducing DFFA-like effector protein C CIDE-3 CIDEX Fat-specific protein FSP27 homolog FLJ20871 Fsp27 FSP27fat specific protein 27

Research Areas for CIDEC

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
DNA Repair