Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Species: Hu
Applications: WB
Species: Mu
Applications: AC
Species: Hu
Applications: AC
Description
Apoptosis is related to many diseases and induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is expressed in many tissues.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
1149 |
| Alternate Names |
- cell death activator CIDE-A
- cell death-inducing DFFA-like effector aCIDE-A
|
Research Areas for CIDEA
Find related products by research area and learn more about each of the different research areas below.
Apoptosis
