Applications: WB, ICC/IF, IHC, IHC-P, IF
Host: Rabbit Polyclonal
CHTF8 encodes a short protein that forms part of the Ctf18 replication factor C (RFC) complex that occurs in both yeast and mammals. The heteroheptameric RFC complex plays a role in sister chromatid cohesion and may load the replication clamp PCNA (proliferating cell nuclear antigen) onto DNA during DNA replication and repair. This gene is ubiquitously expressed and has been shown to have reduced expression in renal and prostate tumors. Alternative splicing results in multiple variants encoding different isoforms. This gene has a pseudogene on chromosome X. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 4 encode the same isoform (A).
|Product By Gene ID
- chromosome transmission fidelity protein 8 homolog
- DERPCchromosome transmission fidelity factor 8 homolog
- Decreased expression in renal and prostate cancer protein
- CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
Pathways for CHTF8
View related products by pathway and learn more about each of the pathways below.Cell Growth
Bioinformatics Tool for CHTF8
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