CETP Products

Description

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Bioinformatics

Entrez	1071 Human
Uniprot	AAH25739 Human AAH25739.1 Human NM_000078 Human NP_000069.2 Human P11597 Human
Product By Gene ID	1071
Alternate Names	cholesteryl ester transfer protein cholesteryl ester transfer protein, plasma HDLCQ10 Lipid transfer protein I

Research Areas for CETP

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism