CD45.1 Products

CD45.1 Antibody (A20) [Alloph ...
CD45.1 Antibody (A20) [Allophycocy...
Species: Mu
Applications: Flow
Conjugate Catalog # Availability Size Price
CD45.1 Antibody (A20) [Alexa ...
CD45.1 Antibody (A20) [Alexa Fluor...
Species: Mu
Applications: Flow
Conjugate Catalog # Availability Size Price


The CD45 antigen is an essential regulator of leukocyte activation and development, and is now known to be a protein tyrosine phosphatase, e.g. CD45 is able to dephosphorylate the Src family of protein kinases. (1, 2) This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling and Fc receptor stimulation. (1, 2) The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variant CD45R, and as allelic forms CD45.1/Ly-5.1 and CD45.2/Ly-5.2. The former arises as a result of alternative splicing of different exons. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. (3, 4) The monoclonal antibody A20 recognizes all mouse leukocytes expressing the CD 45.1 allotype.


Entrez Rat
Product By Gene ID 5788
Alternate Names
  • EC
  • CD45R
  • T200 leukocyte common antigen
  • B220
  • T200 glycoprotein
  • CD45 antigen
  • receptor-type tyrosine-protein phosphatase C
  • L-CA
  • T200receptor type, c polypeptide
  • LY5
  • protein tyrosine phosphatase, receptor type, C

Research Areas for CD45.1

Find related products by research area and learn more about each of the different research areas below.

Mesenchymal Stem Cell Markers
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Stem Cell Markers

Bioinformatics Tool for CD45.1

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