CD3 zeta Products

Antibodies
CD3 zeta Antibody (4A12-F6)
CD3 zeta Antibody (4A12-F6)
H00000919-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, IP
Host: Mouse Monoclonal
CD3 zeta Antibody (4B10)
CD3 zeta Antibody (4B10)
NBP1-42561
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
CD3 zeta Antibody
CD3 zeta Antibody
H00000919-D01P
Species: Hu, Mu, Rt
Applications: WB, ELISA, PLA
Host: Rabbit Polyclonal
Antibody Pairs
CD3 zeta Antibody Pair
CD3 zeta Antibody Pair
H00000919-PW1
Species: Hu
Applications: WB, IP
Lysates
CD3 zeta Overexpression Lysat ...
CD3 zeta Overexpression Lysate (Na...
NBL1-08925
Applications: WB
CD3 zeta Overexpression Lysat ...
CD3 zeta Overexpression Lysate (Na...
NBP2-10689
Applications: WB
CD3 zeta Overexpression Lysat ...
CD3 zeta Overexpression Lysate (De...
H00000919-T01
Applications: WB
Proteins
CD3 zeta Recombinant Protein
CD3 zeta Recombinant Protein
NBP2-22747
Species: Hu
Applications: PAGE
CD3 zeta Recombinant Protein
CD3 zeta Recombinant Protein
H00000919-P01
Species: Hu
Applications: WB, ELISA, PA
CD3 zeta Recombinant Protein ...
CD3 zeta Recombinant Protein Antigen
NBP1-85750PEP
Species: Hu
Applications: AC
RNAi
CD3 zeta RNAi
CD3 zeta RNAi
H00000919-R03
Species: Hu
CD3 zeta RNAi
CD3 zeta RNAi
H00000919-R04
Species: Hu

Description

CD3 (Cluster of Differentiation 3) is a complex of proteins that associates directly with the T cell antigen receptor (TCR). Antigen binding to the TCR leads to IL-2 secretion via activation of a tyrosine phosphorylation pathway and a phospholipase C (PLC) pathway, in turn activating protein kinase C. CD3 is composed of five invariant polypeptide chains that associate to form three dimers. The five invariant chains of CD3 are labeled gamma, delta, epsilon, zeta, and eta. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Loss of the zeta chain results in the synthesis of unstable TCRs. A decrease of CD3 zeta has been described in T cells from patients with cancer, lupus and chronic infectious diseases.

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 919
Alternate Names
  • CD3z antigen, zeta polypeptide (TiT3 complex)
  • T-cell surface glycoprotein CD3 zeta chain
  • CD247 antigen
  • T-cell antigen receptor complex, zeta subunit of CD3
  • CD3Q
  • CD247 antigen, zeta subunit
  • CD3H
  • TCRZCD3-ZETA
  • CD3ZT-cell receptor T3 zeta chain
  • T3Z
  • CD247 molecule

Pathways for CD3 zeta

View related products by pathway and learn more about each of the pathways below.

Pathogenesis
Cell Development
Methylation
Cell Activation
Reverse Transcription
Cell Cycle
Mitosis
T Cell Activation
Dna Methylation
Secretion

Research Areas for CD3 zeta

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
CD Markers
Cell Biology
Diabetes Research
Immunology
Phospho-Specific
Protein Kinase
Signal Transduction
Tyrosine Kinases

PTMs for CD3 zeta

Learn more about PTMs related to CD3 zeta.

Demethylation
Phosphorylation
Methylation

Bioinformatics Tool for CD3 zeta

Discover related pathways, diseases and genes to CD3 zeta. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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