Species: Hu, Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Po
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Ch
Applications: ELISA
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
CD3 delta is encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq]
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
915 |
Alternate Names |
- CD3 antigen, delta subunit
- CD3d antigen
- CD3d antigen, delta polypeptide (TiT3 complex)
- CD3d molecule, delta (CD3-TCR complex)
- CD3-DELTA
- T3DOKT3, delta chain
- T-cell receptor T3 delta chain
- T-cell surface glycoprotein CD3 delta chain
|