CBS Products

Description

CBS is encoded by this gene is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects many organs and tissues, including the eyes and the skeletal, vascular and central nervous systems.

Bioinformatics

Entrez	875 Human 12411 Mouse 24250 Rat
Uniprot	P35520 Human AAH10242 Human NP_000062 Human NP_000062.1 Human AAH11381 Human AAH11381.1 Human NM_000071 Human
Product By Gene ID	875
Alternate Names	EC 4.2.1.2210Beta-thionase cystathionine-beta-synthase

Diseases related to CBS

Discover more about diseases related to CBS.

Hyperhomocysteinemia
5,10-methylenetetrahydrofolate Reductase Deficiency
Homocystinuria
Cystathionine Beta-synthase Deficiency Disease
Malignant Neoplasms
Ulcer
Cardiovascular Diseases
Cerebrovascular Accident
Thrombosis
Neoplasms
Infection By Cryptococcus Neoformans
Duodenal Ulcer
Dementia
Vascular Diseases
Alzheimer's Disease
Carcinoma
Helicobacter Infections
Atrophy
Inflammation
Neurodegenerative Disorders

Pathways for CBS

View related products by pathway and learn more about each of the pathways below.

Fermentation
Transsulfuration
Transport
Pathogenesis
Methylation
Secretion
Mating
Localization
Cell Growth
Excretion
Dna Methylation
Cell Cycle
Cell Death
Translation
Vasodilation
Aging
Hemostasis
Glycosylation
Chromosome Breakage
Cognition

Research Areas for CBS

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for CBS

Learn more about PTMs related to CBS.

Methylation
Phosphorylation
Cleavage
Reduction
Oxidation
Nitration
Glycosylation
Hydroxylation
Acylation
Sumoylation
Decarboxylation
Cysteinylation
Amination
Demethylation
Glutathionylation
Phosphorothioation
Deamination
Dephosphorylation
C-mannosylation
Palmitoylation

Bioinformatics Tool for CBS

Discover related pathways, diseases and genes to CBS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.