Cbl-c Products

Antibodies
Cbl-c Antibody
Cbl-c Antibody
NBP1-78063
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Cbl-c Antibody
Cbl-c Antibody
NBP1-02810
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Cbl-c Antibody (4E3)
Cbl-c Antibody (4E3)
NBP2-46072
Species: Hu
Applications: WB, Flow
Host: Mouse monoclonal
Lysates
Cbl-c Overexpression Lysate ( ...
Cbl-c Overexpression Lysate (Native)
NBL1-08738
Applications: WB
Proteins
Cbl-c Recombinant Protein
Cbl-c Recombinant Protein
H00023624-P01
Species: Hu
Applications: WB, ELISA, PA

Description

Cbl-c is also known as signal transduction protein CBL-C, SH3-binding protein CBL-C, CBL-3, and RING finger protein 57. Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl-c (a.k.a. Cbl-3) is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Cbl-c knock out mice show no obvious phenotype. Thus, the physiological role of Cbl-c is not known

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 23624
Alternate Names
  • CBL3
  • Cas-Br-M (murine) ectropic retroviral transforming sequence c
  • signal transduction protein CBL-C
  • CBL-SL
  • SH3-binding protein CBL-C
  • CBL-3
  • RNF57SH3-binding protein CBL-3
  • RING finger protein 57
  • Cas-Br-M (murine) ecotropic retroviral transforming sequence c

Research Areas for Cbl-c

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Markers

PTMs for Cbl-c

Learn more about PTMs related to Cbl-c.

Phosphorylation
Methylation
Ubiquitination
Reduction

Bioinformatics Tool for Cbl-c

Discover related pathways, diseases and genes to Cbl-c. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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