CARD9 Products

Description

Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-kB. CARD9 is an upstream activator of BCL-10 and NF-kB signaling.

Bioinformatics

Entrez	64170 Human
Uniprot	AAH08877 Human AAH08877.1 Human AF311287 Human NP_434700 Human NP_434701 Human
Product By Gene ID	64170
Alternate Names	CANDF2 caspase recruitment domain family, member 9 caspase recruitment domain-containing protein 9 hCARD9

Research Areas for CARD9

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Apoptosis