CAR/NR1I3 Products

Antibodies
CAR/NR1I3 Antibody (N4111)
CAR/NR1I3 Antibody (N4111)
PP-N4111-00
Species: Hu
Applications: WB, IHC, IP
Host: Mouse Monoclonal
CAR/NR1I3 Antibody (331930)
CAR/NR1I3 Antibody (331930)
MAB3724
Species: Hu, Mu
Applications: WB
Host: Rat Monoclonal
CAR/NR1I3 Antibody (1C6)
CAR/NR1I3 Antibody (1C6)
NBP2-46226
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
Antibody Pairs
CAR/NR1I3 Antibody Pair
CAR/NR1I3 Antibody Pair
H00009970-PW2
Species: Hu
Applications: WB, IP
Lysates
CAR/NR1I3 Overexpression Lysa ...
CAR/NR1I3 Overexpression Lysate (N...
NBP2-07791
Applications: WB
CAR/NR1I3 Overexpression Lysa ...
CAR/NR1I3 Overexpression Lysate (N...
NBP2-08458
Applications: WB
CAR/NR1I3 Overexpression Lysa ...
CAR/NR1I3 Overexpression Lysate (N...
NBP2-08456
Applications: WB
Proteins
CAR/NR1I3 Recombinant Protein ...
CAR/NR1I3 Recombinant Protein
H00009970-P01
Species: Hu
Applications: WB, ELISA, PA
CAR/NR1I3 Partial Recombinant ...
CAR/NR1I3 Partial Recombinant Protein
H00009970-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
CAR/NR1I3 RNAi
CAR/NR1I3 RNAi
H00009970-R01
Species: Hu

Description

NR1I3 encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 9970
Alternate Names
  • orphan nuclear hormone receptor
  • nuclear receptor subfamily 1 group I member 3
  • MGC97209
  • constitutive active receptor
  • MGC97144
  • MGC150433
  • Orphan nuclear receptor MB67
  • Constitutive androstane receptor
  • Constitutive active response
  • Constitutive activator of retinoid response
  • MB67
  • CARCAR1
  • nuclear receptor subfamily 1, group I, member 3

Research Areas for CAR/NR1I3

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for CAR/NR1I3

Learn more about PTMs related to CAR/NR1I3.

Phosphorylation
Oxidation
Dephosphorylation
Acetylation

Bioinformatics Tool for CAR/NR1I3

Discover related pathways, diseases and genes to CAR/NR1I3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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