CaMKK2 Products

Description

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq]

Bioinformatics

Entrez	10645 Human
Uniprot	AAH26060 Human NP_006540 Human NM_172226 Human NP_757380 Human NP_705719 Human NP_705719.2 Human Q96RR4 Human
Product By Gene ID	10645
Alternate Names	CaM-KK 2 EC 2.7.11 CaM-kinase kinase beta CaMKK beta CaM-kinase kinase 2 EC 2.7.11.17 Calcium/calmodulin-dependent protein kinase kinase beta CAMKK beta protein MGC15254 calcium/calmodulin-dependent protein kinase kinase 2 CAMKK KIAA0787calcium/calmodulin-dependent protein kinase beta CAMKKBCaMKK 2 CaM-KK beta calcium/calmodulin-dependent protein kinase kinase 2, beta

Diseases related to CaMKK2

Discover more about diseases related to CaMKK2.

Malignant Neoplasms
Nervousness
Neoplasms
Impaired Glucose Tolerance
Inflammation
Obesity
Anxiety Disorders
Prostatic Neoplasms
Insulin Resistance
Malignant Neoplasm Of Prostate
Cholangiocarcinoma
Learning Disorders
Sclerosis
Malnutrition
Aneuploidy
Malignant Tumor Of Cervix
Severe Combined Immunodeficiency

Pathways for CaMKK2

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Glucose Homeostasis
Cell Proliferation
Localization
Rna Interference
Anaphase
Cell Cycle
Long-term Memory
Granulocyte Differentiation
Cell Migration
Brain Development
Macroautophagy
Mating
Estrus
Insulin Secretion
Cell Development
Mitosis
Energy Homeostasis
Dna Replication
Short-term Memory
Cell Death

Research Areas for CaMKK2

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Protein Kinase

PTMs for CaMKK2

Learn more about PTMs related to CaMKK2.

Phosphorylation
Oxidation

Bioinformatics Tool for CaMKK2

Discover related pathways, diseases and genes to CaMKK2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.