Calnexin Products

Antibodies
Calnexin Antibody
Calnexin Antibody
NB100-1965
Species: Hu, Mu, Rt, Po, Av, Bv, Ch, Dr, GP, Rb, Sh, Xp, Ze, Canine
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Calnexin Antibody
Calnexin Antibody
NB100-1974
Species: Hu, Mu, Rt, Ha, Avian, Bovine, Canine, Chicken, Drosophila, Guinea Pig, Primate, Porcine, Rabbit, Sheep, Xenopus
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
Calnexin Overexpression Lysat ...
Calnexin Overexpression Lysate (Na...
NBP2-11041
Applications: WB
Calnexin Overexpression Lysat ...
Calnexin Overexpression Lysate (Na...
NBP2-10767
Applications: WB
Proteins
Calnexin Recombinant Protein
Calnexin Recombinant Protein
NBP1-30235
Species: Hu
Applications: PAGE
Calnexin Recombinant Protein ...
Calnexin Recombinant Protein Antigen
NBP1-85520PEP
Species: Hu
Applications: AC
Calnexin Recombinant Protein ...
Calnexin Recombinant Protein Antigen
NBP1-85519PEP
Species: Hu
Applications: AC
RNAi
Calnexin RNAi
Calnexin RNAi
H00000821-R01
Species: Hu
Calnexin RNAi
Calnexin RNAi
H00000821-R02
Species: Hu

Description

Calnexin, an abundant approx. 90kDa integral protein of the endoplasmic reticulum, is also referred to as IP90, p88 and p90 (1). It consists of a large 50kDa N-terminal calcium-binding luminal domain, a single transmembrane helix and a short acidic cytoplasmic tail (2, 3). Unlike its ER counterparts which have a KDEL sequence on their Cterminus to ensure ER retention (4), calnexin has positively charged cytosolic residues that do the same thing (3). Most ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into mulit-subunit proteins. Calnexin together with calreticulin, plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their monoglycosylated glycans (5, 6). Calnexin has also been shown to associate with the major histocompatability complex class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin (7).

Bioinformatics

Entrez Human
Mouse
Rat
Canine
Uniprot Human
Human
Human
Human
Rat
Canine
Product By Gene ID 821
Alternate Names
  • p90
  • P90
  • CNX
  • IP90FLJ26570
  • Major histocompatibility complex class I antigen-binding protein p88
  • calnexin

Pathways for Calnexin

View related products by pathway and learn more about each of the pathways below.

Fertilization
Regeneration
Reverse Transcription
Cell Proliferation
Translation
Cell Death
Sperm Capacitation
Mating
Wound Healing
Rna Processing
Autophagy

Research Areas for Calnexin

Find related products by research area and learn more about each of the different research areas below.

ER Markers
Neuroscience
Phospho-Specific
Sensory Systems
Unfolded Protein Response
Vision

Bioinformatics Tool for Calnexin

Discover related pathways, diseases and genes to Calnexin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Calnexin Blog Posts

Check out the latest blog posts on Calnexin.
Calnexin - an ER chaperone that folds the cell's glycoproteins
Calnexin is an abundant 90kDa chaperone protein that resides in the membrane of the endoplasmic reticulum. Calnexin and the related calreticulin protein function together to ensure the proper folding of glycoproteins. By binding to partially folded...    Read more.
Read more Calnexin related blogs.