Cadherin-8 Products

Description

The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. cadherin-8 expression has been seen in mouse thymus tissue as well as in specific subdivisions of the developing central nervous system. It plays a potential role in brain morphology.

Bioinformatics

Entrez	1006 Human 84408 Rat
Uniprot	NM_001796 Human NP_001787 Human NP_001787.2 Human P55286 Human
Product By Gene ID	1006
Alternate Names	cadherin 8, type 2 cadherin-8 Nbla04261 putative protein product of Nbla04261