CACNA2D4 Products

Antibodies
CACNA2D4 Antibody
CACNA2D4 Antibody
NBP1-85920
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
CACNA2D4 Antibody
CACNA2D4 Antibody
NBP1-68992
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
CACNA2D4 Antibody
CACNA2D4 Antibody
NBP1-98469
Species: Mu
Applications: WB
Host: Rabbit Polyclonal
Proteins
CACNA2D4 Recombinant Protein ...
CACNA2D4 Recombinant Protein Antigen
NBP1-85920PEP
Species: Hu
Applications: AC
RNAi
CACNA2D4 RNAi
CACNA2D4 RNAi
H00093589-R01
Species: Hu
Applications: RNAi, RNAi SP
CACNA2D4 RNAi
CACNA2D4 RNAi
H00093589-R03
Species: Hu
Applications: RNAi, RNAi SP
CACNA2D4 RNAi
CACNA2D4 RNAi
H00093589-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

FUNCTION: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Defects in CACNA2D4 are the cause of retinal cone dystrophy 4 (RCD4). RCD4 is characterized by minimal symptoms except for slowly progressive reduction in visual acuity.; Tissue specificity: Predominantly expressed in certain types of endocrine cells. Present in the Paneth cells of the small intestine. Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophiles of the pituitary. Present at low level in some brain regions such as the cerebellum (at protein level).; Subcellular location: Membrane; Single-pass type I membrane protein; Miscellaneous: In contrast to CACNA2D1 and CACNA2D2, it does not bind gabapentin, an antiepileptic drug.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 93589
Alternate Names
  • voltage-gated calcium channel alpha(2)delta-4 subunit
  • voltage-dependent calcium channel subunit alpha-2/delta-4
  • RCD4
  • Voltage-gated calcium channel subunit alpha-2/delta-4
  • calcium channel, voltage-dependent, alpha 2/delta subunit 4

Pathways for CACNA2D4

View related products by pathway and learn more about each of the pathways below.

Methylation
Cell Proliferation
Signal Transmission
Cell Growth

Research Areas for CACNA2D4

Find related products by research area and learn more about each of the different research areas below.

Vision

PTMs for CACNA2D4

Learn more about PTMs related to CACNA2D4.

Methylation

Bioinformatics Tool for CACNA2D4

Discover related pathways, diseases and genes to CACNA2D4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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