CACNA2D1 Products

Antibodies
CACNA2D1 Antibody (20A)
CACNA2D1 Antibody (20A)
Species: Hu, Mu, Rt, Po, GP, Rb
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
CACNA2D1 Antibody
CACNA2D1 Antibody
NBP1-86683
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
CACNA2D1 Antibody
CACNA2D1 Antibody
NB100-60951
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
CACNA2D1 Overexpression Lysat ...
CACNA2D1 Overexpression Lysate (Na...
NBP2-08998
Applications: WB
Proteins
CACNA2D1 Recombinant Protein ...
CACNA2D1 Recombinant Protein Antigen
NBP1-86682PEP
Species: Hu
Applications: AC
CACNA2D1 Recombinant Protein ...
CACNA2D1 Recombinant Protein Antigen
NBP1-86683PEP
Species: Hu
Applications: AC
RNAi
CACNA2D1 RNAi
CACNA2D1 RNAi
H00000781-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The CACNA2D1 gene encodes a voltage-dependent calcium channel subunit alpha-2/delta-1 protein that exists in 5 isoforms: isoform 1: 1,103 amino acids long, 124 kDA; isoform 2: 1,091 amino acids long, 123 kDA; isoform 3: 1,086 amino acids long, 122 kDA; isoform 4: 1,079 amino acids long, 121 kDA; and isoform 5: 1,084 amino acids long, 122 kDA. These proteins are critical in calcium current density and in activation and inactivation kinetics of the calcium channel. Additionally, these proteins function in excitation-contraction coupling. The CACNA2D1 gene participates in transcription of the CREB pathway, the caspase cascade, Fc-GammaR pathway, BMP and PDGF pathways, MAPK signaling pathway, and cardiac muscle contraction. It is known to interact with genes DLG4, CACNA1C, CACNA1D, CACNA1F, and YWHAB. The CACNA2D1 gene is associated with neuroblastoma, heart blocks, liver disease, parkinson's disease, dementia, malignant hyperthermia susceptibility, lambert-eaton myasthenic syndrome, timothy syndrome, peripheral neropathy, and fatty liver disease.

Bioinformatics

Entrez Human
Mouse
Rat
Rabbit
Uniprot Human
Human
Human
Product By Gene ID 781
Alternate Names
  • CACNA2
  • MHS3
  • CCHL2A
  • voltage-dependent calcium channel subunit alpha-2/delta-1
  • Voltage-gated calcium channel subunit alpha-2/delta-1
  • CACNL2Adihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit
  • calcium channel, L type, alpha 2 polypeptide
  • calcium channel, voltage-dependent, alpha 2/delta subunit 1

PTMs for CACNA2D1

Learn more about PTMs related to CACNA2D1.

Cleavage
Methylation
Gpi Anchoring
Phosphorylation
Glycosylation

Bioinformatics Tool for CACNA2D1

Discover related pathways, diseases and genes to CACNA2D1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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